The 2-Minute Rule for cees dekker
The 2-Minute Rule for cees dekker
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‘The 2nd is nanopores, which is our oldest line of exploration and that has now resulted in DNA sequencers depending on nanopores. We pull unique DNA strands by way of a nanopore and may then read through off the nucleotide sequence. Very not too long ago, we even managed to read out one protein for the first time applying This method. But this line of research is not just about establishing instruments, but also about serious Organic inquiries.
1996, initially mesoscopic charge density waves products; and first electrical measurements on one metallic nanocluster amongst nanoelectrodes
Within the similar time, the group of Paul McEuen, who was then centered within the College of California, Berkeley, showed very similar final results on ropes of bundled nanotubes. According to the wrapping angle, nanotubes can come in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently confirmed using scanning tunnelling spectroscopy experiments.
Deposition and atomic pressure microscopy of unique phthalocyanine polymers concerning nanofabricated electrodes
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The coiled-coil on the human Rad50 DNA restore protein incorporates distinct segments of improved adaptability
We form microorganisms into types that deviate from their all-natural phenotype. Specifically, I will show our power to form Reside E. coli germs into novel styles which include rectangles, squares, triangles and circles.
Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in the cooperative manner
Knowledge elementary procedures regulating the spatial and ceesdekker dynamic organisation on the DNA in live cells.
‘The fantastically subtle way wherein features in character operate in no way ceases to amaze me. If we resolve the puzzle of how life arrived into currently being, I count on that my amazement in the complexity of generation will likely have enhanced and with it my awe for your greatness of the Creator.’
Given that 2000 he moved to one-molecule biophysics and nanobiology, with investigate from scientific studies of DNA loop extrusion and supercoiling to DNA translocation by way of nanopores. Much more not long ago his research has centered on researching chromatin construction and cell division with microorganisms on chip, when he can be attempting to in the long run Make artificial cells from The underside up.
Cees Dekker is Distinguished University Professor at TU Delft. Educated as being a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His present research concentrates on (i) nanopores for protein sequencing; (ii) chromosome composition, specifically SMC motor protein; and (iii) creating a residing synthetic mobile from lifeless molecules. Dekker can be an elected member with the KNAW and fellow to your APS as well as IOP.
Developments in nanotechnology within the 1990s produced creating electronic gadgets from single molecules a chance. Cees Dekker recounts how his group developed a space-temperature transistor depending on just one carbon nanotube.
2004, discovery of latest physics in translocation of DNA via nanopores; to start with experimental examine of ions conduction in nanofluidic channels; initial electrochemistry with unique solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initially biophysics characterization on the mechanical properties of double-stranded RNA; and initially single-molecule analyze of DNA translocation by a restriction-modification enzyme.